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Azure Regions leverage a low-latency interconnect to keep them all running together smoothly. IT is important to remember this point from a solution architecture perspective.
We can have multiple regions and something referred to as region pair set up → Cross-Region Replication for disaster recovery.
Azure Region is referred as a geography → data has to remain within a specific geogpraphy or regarding other compliance requirements in terms of where services and data are allowed to reside.
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2- Availability Zones
This is physically separate location within a region
We can pin some services to a specific availability zone.